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8주간의 유산소 운동강도에 따른 어린 생쥐의 체중, 식이효율, 뇌의 비만조절 인자(AMPK), 활성산소(MDA), 항산화효소(SOD)의 차이

 Differences in Body Weight, Dietary Efficiency, Brain Obesity Control Factor (AMPK), Reactive Oxygen Species (MDA), and Antioxidant Enzymes (SOD) in Young Mice According to the Intensity of Aerobic Exercise for 8 Weeks

Journal of Korean Biological Nursing Science 2021년 23권 3호 p.247 ~ 255
KMID : 0869120210230030247
전미양 ( Jeon Mi-Yang ) - Gyeongsang National University College of Nursing

Abstract

Purpose: The goal of this study was to see how different aerobic exercise intensities affected AMP-activated protein kinase (AMPK), reactive oxygen, and antioxidant enzymes in young mice during an 8-week period.

Methods: Forty male C57BL/6 mice, aged seven weeks, were randomly assigned to one of four groups: control (n= 10), low-intensity exercise (n= 10), moderate-intensity exercise (n= 10), and high-intensity exercise (n= 10). For eight weeks, aerobic activity was performed once a day for 35?40 minutes, five days a week. The data were analyzed using descriptive statistics, analysis of variance (ANOVA), chi-squared tests, and the Tukey test in the SPSS/WIN 25.0 program.

Results: Weight (p= .001) was substantially different between the moderate-intensity exercise group and the control group in AMPK (p< .001). In addition, there were no significant differences between the moderate-intensity exercise group and the control group in reactive oxygen malondialdehyde (MDA) levels (p= .136) and antioxidant enzyme superoxide dismutase (SOD) levels (p= .521).

Conclusion: These findings suggest that moderate-intensity aerobic exercise increased AMPK activation and helped young mice shed weight
KeyWords
생쥐, 운동, 항산화효소, 활성산소, 5’아데노신 1인산염 활성화 단백질 인산화효소
Antioxidants, AMP-activated protein kinases, Reactive oxygen species, Exercise, Mice
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등재저널 정보
학술진흥재단(KCI) KoreaMed